Yuniarto, Prayoga Fery (2013) OPTIMASI FORMULA GEL BUAH APEL HIJAU (Pyrus malus L.) SEBAGAI ANTIOKSIDAN DENGAN KOMBINASI BASIS CARBOPOL 940 DAN GLISERIN SECARA SIMPLEX LATTICE DESIGN. Skripsi thesis, Universitas Setia Budi Surakarta.
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Abstract
Apple is suspected has an antioxidant. The use of apple fruit directly considered less practical, so that it made the gel preparations. And then it use optimation by Simplex Lattice Design method so get the most optimum antioxidant gel. This research purpose for know the efficacy of apple optimation gel as an antioxidant. Maceration extract made of gel with components carbopol 940(C) and glycerin(G) so that get three formulas, F1 (100%C), F2 (50%C, 50%G), dan F3 (100%G) and then optimation by viscosity, adhesion, and dispersive power. Simplex Lattice Design method with use program design- expert 8.0.6.1. Research antioxidant activity of optimum gel by method of DPPH. Antioxidant activity calculated by λ maximum and operating time so that get IC50 values by probit analysis. Optimation mixture between carbopol 940 and gliserin as components is carbopol 2.448 and glycerin 2.552. The result of t-test of viscosity, adhesion, and dispersive power showed no significant difference between the predictions with actual experimental result. The result showed optimum gel of apple fruit has antioxidant activity amounted to 151,43 ppm. Storage time affected the viscosity of the gel which tends to decrease during the months of storage. Keyword: apple fruit, carbopol 940, glycerin, Simplex Lattice Design, antioxidant
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | apple fruit, carbopol 940, glycerin, Simplex Lattice Design, antioxidant |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | B Supri Yadi |
| Date Deposited: | 20 Feb 2020 06:55 |
| Last Modified: | 20 Feb 2020 06:55 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/3009 |
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