UJI AKTIVITAS ANTIOKSIDAN LOTION EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) DENGAN METODE DPPH (1,1-difenil-2-pikrilhidrazil)

Istiqomah, Nur Azmi (2019) UJI AKTIVITAS ANTIOKSIDAN LOTION EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) DENGAN METODE DPPH (1,1-difenil-2-pikrilhidrazil). Skripsi thesis, Universitas Setia Budi.

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Abstract

Kersen leaves (Muntingia calabura L.) contain flavonoids, phenolics and saponins. Flavonoids compounds have antioxidant activity. This study aims to determine the effect of variations in ethanol extract of kersen leaves (Muntingia calabura L.) toward antioxidant activity and the stability of the physical quality of lotion formula. The ethanol extract of kersen leaf (Muntingia calabura L.) was obtained by maceration method using ethanol 70%. Lotion formula was made in 5 formulas are formula 1 (negative control), formula 2,3,4 (contained extract of 10%, 15% and 20%), and formula 5 (positive control). Determination of antioxidant activity was carried out by the DPPH method by calculating the IC50 value. Lotion formula are also carried out, physical quality tests include organoleptic tests, homogeneity, viscosity, dispersion, cream type test, adhesion, pH and cycling test stability. The results showed that the extract ethanol of kersen leaves (Muntingia calabura L.) had antioxidant activity with IC50 43,003 ppm. Lotion formula extract ethanol of kersen leaves (Muntingia calabura L.) which has stongest antioxidant activity then followed by formula 4, 3, 2 with IC50 206.126 ppm, 223.703 ppm, 314.458 ppm. Based on results indicate that variations in the concentration of ethanol extract of kersen leaves (Muntingia calabura L.) can affect the antioxidant activity of lotion formula. Keywords: antioxidant, DPPH, extract ethanol of kersen leaves (Muntingia calabura L.), lotion.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	antioxidant, DPPH, extract ethanol of kersen leaves (Muntingia calabura L.), lotion.
Subjects:	Q Science > QK Botany
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	12 Nov 2019 07:36
Last Modified:	12 Nov 2019 07:36
URI:	http://repo.setiabudi.ac.id/id/eprint/3783

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