UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL, FRAKSI n-HEKSAN, ETIL ASETAT DAN AIR DARI DAUN BELIMBING WULUH (Averrhoa bilimbi L.) TERHADAP BAKTERI Shigella dysenteriae

Dayani, Gracesya Indah (2018) UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL, FRAKSI n-HEKSAN, ETIL ASETAT DAN AIR DARI DAUN BELIMBING WULUH (Averrhoa bilimbi L.) TERHADAP BAKTERI Shigella dysenteriae. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Belimbing wuluh leaves (Averrhoa bilimbi L.) is a plant which is used empirically as a medicine for dysentery. The chemical contents of belimbing wuluh leaves are flavonoids, saponins and tannin. This research was conducted to know the antibacterial activities of ethanol extract, n-hexane fraction, ethyl acetate and water from belimbing wuluh leaves (Averrhoa bilimbi L.), the three most active fractions, and Minimum Inhibition Concentration and Minimum Kill Concentration from active fraction toward Shigella dysenteriae. The extraction of belimbing wuluh leaves used maceration method with 70% of ethanol solvent, and then it was fractionated by using n-hexane solvent, ethyl acetate and water. The results of extraction and fractionation were tested of antibacterial activity toward Shigella dysenteriae using diffusion method with 50%, 25%, 12,5% concentrations and dilution method with 50%, 25%, 12,5%, 6,25%, 3,12 %, 1,56%, 0,78%, 0,39%, 0,19% and 0,09% concentrations. The test result of diffusion method showed that ethyl acetate fraction has the most active inhibitory effect on Shigella dysenteriae which is 12,43 mm at concentration 50%. Minimum Kill Concentration (MKC) ethyl acetate fraction toward Shigella dysenteriae is concentration 12,5% by using dilution liquid method. Key words: belimbing wuluh leaves (Averrhoa bilimbi L.), Shigella dysenteriae, antibacterial activity test, fraction

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	belimbing wuluh leaves (Averrhoa bilimbi L.), Shigella dysenteriae, antibacterial activity test, fraction
Subjects:	Q Science > QK Botany
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	23 Feb 2019 02:30
Last Modified:	23 Feb 2019 02:30
URI:	http://repo.setiabudi.ac.id/id/eprint/400

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