UJI AKTIVITAS ANTI AGING SEDIAAN EMULGEL MINYAK JINTAN HITAM (Nigella sativa L.) PADA PUNGGUNG KELINCI NEW ZEALAND (Orictolagus cuniculus) YANG DIPAPAR SINAR UV-A

Debiana, Tia Sarah (2021) UJI AKTIVITAS ANTI AGING SEDIAAN EMULGEL MINYAK JINTAN HITAM (Nigella sativa L.) PADA PUNGGUNG KELINCI NEW ZEALAND (Orictolagus cuniculus) YANG DIPAPAR SINAR UV-A. Skripsi thesis, Universitas Setia Budi.

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Abstract

UV A exposure can trigger the formation of free radicals which causes skin aging. The effect of free radicals can be prevented with antioxidant. Black cumin oil (Nigella sativa L.) compouns contained that has antioxidant activity. Emugel formulations was made to facilitate the application. The research was conducted to determine activity of emulgel from black cumin oil as anti aging in vivo using rabbits that UV A rays exposed. Black cumin oil (Nigella sativa L.) was characterized and identified. Black cumin oil was formulated into emulgel with concentrations 10,15, dan 20%, than tasted for physical quality and stability. Anti aging activity tests on 5 rabbits that had their back shaved and induced UV A for 2 weeks, then they were given treatment for 28 days. Persentage of collagen, elasticity, and moisture were observed using skin analyzer. The results showed that emugel from black cumin has good physical quality and stability. The primary irritation test showed emulgel was very slightly irritating. Anti aging activity test showed emulgel from black cumin oil with concentration of 20% gave great anti aging efect. Keywords : anti aging activity; black cumin oil; emulgel; skin analyzer

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	anti aging activity; black cumin oil; emulgel; skin analyzer
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	05 Aug 2022 01:35
Last Modified:	05 Aug 2022 01:35
URI:	http://repo.setiabudi.ac.id/id/eprint/5050

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