UJI AKTIVITAS ANTIBAKTERI SEDIAAN SERUM EKSTRAK ETANOL DAUN SIRIH HIJAU (Piper betle L.) TERHADAP BAKTERI Staphylococcus aureus

Nugrahini, Diah Ratri (2022) UJI AKTIVITAS ANTIBAKTERI SEDIAAN SERUM EKSTRAK ETANOL DAUN SIRIH HIJAU (Piper betle L.) TERHADAP BAKTERI Staphylococcus aureus. Skripsi thesis, Universitas Setia Budi.

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Abstract

Acne is a skin infection caused by S. aureus bacteria. Green betel leaf (Piper betle L.) is a plant that has antibacterial activity. One of the preparations for anti-acne is serum. The purpose of this study was to determine the antibacterial activity of serum preparations of green betel leaf extract (Piper betle L.). Green betel leaf extraction process using the maceration method. Testing the antibacterial activity of extracts and serum preparations of green betel leaf on S. aureus bacteria using the diffusion method. The serum formulation in this study used extract concentrations of 5%, 10% and 15% to see the physical quality and xviii stability using the cycling test method. Data analysis used the Shapiro Wilk method. The results of this study were green betel leaf extract serum had good physical qualities including organoleptic tests, homogeneity, pH, viscosity and dispersibility and stability during the storage period of the preparation. Serum with green betel leaf extract concentrations of 5%, 10% and 15% had antibacterial activity against S. aureus with inhibition zones of 13.17±0.15 mm, 14.23±15 mm, and 15.13±0, 15 mm. Green betel leaf extract serum with a concentration of 15% had the most effective antibacterial activity against S. aureus bacteria. Keywords : Antibacterial; Piper betle L.;Serum; Diffusion; Variation of extract concentration

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Antibacterial; Piper betle L.;Serum; Diffusion; Variation of extract concentration
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	29 Sep 2022 04:38
Last Modified:	29 Sep 2022 04:38
URI:	http://repo.setiabudi.ac.id/id/eprint/5279

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