Putri, Anni Salsabila (2022) FORMULASI SEDIAAN MASKER GEL PEEL OFF BELIMBING WULUH (Averrhoa Bilimbi L.) DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP Propionibacterium acnes SERTA UJI KEAMANAN DENGAN GELLING AGENT PVA PADA KULIT KELINCI. Skripsi thesis, Universitas Setia Budi.
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Abstract
Disruption of the hormonal balance of facial skin causes acne. One way to protect facial skin is with a peel off gel mask. Wuluh star fruit contains flavonoids which function as antibacterial. This study aims to make a peel-off gel mask preparation of star fruit extract, with good physical quality, and tested its activity against Propionibacterium acnes, and tested its safety on rabbit skin. The experimental method was used to test the antibacterial activity against Propionibacterium acnes. There were six formulations of peel off starfruit peel off gel mask, evaluated for physical quality test, antibacterial activity test against Propionibacterium acnes, and irritation test on rabbit skin. The test results were analyzed, obtained variations in the concentration of extracts and PVA can be formulated into a peel off gel mask preparation with good physical quality on organoleptic parameters, homogeneity, pH, drying time, and viscosity. Then the extract of starfruit (Averrhoa Bilimbi L.) 20% and PVA 10% had an inhibitory diameter of 25 mm, extract 25% and PVA 12% had an inhibitory diameter of 26.67 mm, and extract 30% and PVA 14% had an inhibitory diameter of 29, 33 mm, so that starfruit extract with PVA has antibacterial activity against Propionibacterium acnes. The results of the irritation test of the peel off gel mask preparation showed that the FI to FVI preparations did not irritate the rabbit skin and the formula with good physical quality and antibacterial activity and was not irritating to the skin of the test animals was FVI. Keywords: starfruit extract, PVA, peel off gel mask, Propionibacterium acnes, irritation test on rabbit skin
| Item Type: | Thesis (Skripsi) |
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| Uncontrolled Keywords: | starfruit extract, PVA, peel off gel mask, Propionibacterium acnes, irritation test on rabbit skin |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 09 Nov 2022 07:10 |
| Last Modified: | 09 Nov 2022 07:10 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/5419 |
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