UJI AKTIVITAS EMULGEL EKSTRAK ETANOL DAUN SIRSAK (Annona muricata L.) SEBAGAI TABIR SURYA SECARA IN VITRO

Pratama, Djio Fanni (2022) UJI AKTIVITAS EMULGEL EKSTRAK ETANOL DAUN SIRSAK (Annona muricata L.) SEBAGAI TABIR SURYA SECARA IN VITRO. Skripsi thesis, Universitas Setia Budi.

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Abstract

Exposure to the sun and free radicals with high intensity can cause skin damage that can be prevented with sunscreen preparations. Ethanol extract of soursop leaves (Annona muricata L.) contains flavonoids that are known to have sunscreen activity. This study aims to formulate ethanol extract of soursop leaves (Annona muricata L.) into an emulgel preparation with good physical quality and stability and test the activity of sunscreen in vitro. Ethanol extract of soursop leaves was obtained by maceration using a 96% ethanol solvent. Furthermore, it was formulated in emulgel preparations with a concentration of 2%, 3% and 5% an evaluation of physical quality and stability with a cycling test followed by data analysis using a Paired T-Test. Determination of sun protecting factor (SPF) value of sunscreen emulgel by UV-Vis spectrophotometry. The data were statistically analyzed using One Way Anova. Obtained 4 formulas of emulgel preparation of soursop leaf ethanol extract (Annona muricata L.) with good and stable physical quality, with the SPF value for the emulgel formula the concentration of active substances 2%, 3%, and 5% respectively is 9.816; 15,295 and 30,184. The most active emulgel as a sunscreen is emulgel with an active substance concentration of 5%. Statistical analysis showed that the concentration of the extract affects the emulgel formula and all formulas are stable to temperature and storage length. Keywords: Annona muricata L, emulgel, sunscreen, in-vitro, UV spectrophotometry

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Annona muricata L, emulgel, sunscreen, in-vitro, UV spectrophotometry
Subjects:	R Medicine > RS Pharmacy and materia medica R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 04:18
Last Modified:	30 Nov 2022 04:18
URI:	http://repo.setiabudi.ac.id/id/eprint/5484

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