FORMULASI DAN UJI AKTIVITAS GEL HAND SANITIZER EKSTRAK ETANOL DAUN KELOR (Moringa oleifera) DENGAN KOMBINASI VARIASI Gelling agent TERHADAP BAKTERI Staphylococcus aureus

Adhitya, I Gusti Agung Gede (2022) FORMULASI DAN UJI AKTIVITAS GEL HAND SANITIZER EKSTRAK ETANOL DAUN KELOR (Moringa oleifera) DENGAN KOMBINASI VARIASI Gelling agent TERHADAP BAKTERI Staphylococcus aureus. Skripsi thesis, Universitas Setia Budi.

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Abstract

Transmission of susceptible diseases caused through the skin media by the presence of potentially pathogenic bacteria can be a danger to humans when the number exceeds the limit.is Staphylococcus aureus one of the main bacteria causing skin infections. Moringa leaves (Moringga oleifera) have potential as antibacterial. The purpose of this study was to determine the formula for hand sanitizer with a good combination of carbopol and Na CMC based on the parameters of dispersion, pH, homogeneity, stability and also to determine the formula has good antibacterial activity against Staphylococcus aureus. The method of making Moringa leaf ethanol extract by maceration using 96% ethanol solvent, then the formulation of the preparation using a combination of carbopol and Na CMC concentrations of 1%:1%, 0.2%:0.8%, 0.5%:0.5 %, 0.8%:0.2% Tests of physical quality and stability of the preparation were carried out on the formula to determine the best formula and its antibacterial activity against Staphylococcus aureus.data were statistically analyzed by Shapiro Wilk followed by one way ANOVA and Paired t-test. The results showed that all formulas had good physical quality, but not all formulas had good stability. Formula 3 with concentrations of carbopol and Na CMC 0.8%:0.2% is the best formula in terms of physical quality, stability where there is no significant change in stability but in the anti-bacterial activity test, each formula has the same extract concentration so that it provides an inhibition zone. which was similar to Staphylococcus aureus with an average inhibition zone diameter of 17.25mm, 17.48mm, 17.69 mm, respectively. Keywords: hand sanitizer gel, Moringa (Moringa oleifera) leaf extract, Staphylococcus aureus, antibacterial activity

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	hand sanitizer gel, Moringa (Moringa oleifera) leaf extract, Staphylococcus aureus, antibacterial activity
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 02:58
Last Modified:	30 Nov 2022 02:58
URI:	http://repo.setiabudi.ac.id/id/eprint/5513

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