FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI EMULGEL EKSTRAK DAUN KENIKIR (Cosmos caudatus Kunth.) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923

Fitria, Krismona Rizky Nur (2022) FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI EMULGEL EKSTRAK DAUN KENIKIR (Cosmos caudatus Kunth.) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923. Skripsi thesis, Universitas Setia Budi.

	Text INTISARI ABSTRACT.pdf Download (17kB)
	Text COVER - BAB 1.pdf Download (906kB)
	Text BAB 2.pdf Restricted to Repository staff only Download (160kB) | Request a copy
	Text BAB 3.pdf Restricted to Repository staff only Download (321kB) | Request a copy
	Text BAB 4.pdf Restricted to Repository staff only Download (505kB) | Request a copy
	Text BAB 5.pdf Restricted to Repository staff only Download (13kB) | Request a copy
	Text DAFTAR PUSTAKA.pdf Download (105kB)
	Text LAMPIRAN.pdf Download (335kB)
	Text 1665366037205_krismonas suket 26 sept.pdf Download (22kB)
	Text acc Krismona Rizky Nur Fitria_Form Publikasi.pdf Download (177kB)

Abstract

Acne is a skin disease generally caused by various factors, including food, genetics, hormones, and bacterial infection. The most severe cause of acne that accompanies pus is Staphylococcus aureus. Kenikir leaf contains active compounds, namely flavonoids, saponins, terpenoids, alkaloids, and tannins which have the potential as antibacterial. This study used HPMC as a gelling agent at various concentrations in the emulgel preparation of kenikir leaf extract to know the physical quality and antibacterial activity of Staphylococcus aureus ATCC 25923. Kenikir leaf extraction used maceration method with 96% ethanol solvent, then formulated with 15% kenikir leaf extract concentration and 3% HPMC variation; 3.5%; 4%. Evaluation of emulgel preparations includes organoleptic, homogeneity, spreadability, adhesion, viscosity, pH, stability, determining the emulsion type, cycling test, and antibacterial activity of Staphylococcus aureus ATCC 25923. Data on physical quality tests and antibacterial activity were statistically analyzed using Shapiro Wilk, followed by one-way ANOVA and Pairet t-test. The study's results stated that the emulgel preparation of kenikir leaf extract with variations in HPMC concentrations had good physical quality, stability, and antibacterial activity. The results of the antibacterial activity test against Staphylococcus aureus ATCC 25923 at 3% HPMC concentration of 14.23 mm, 3.5% HPMC concentration of 13.7 mm, and 4% HPMC concentration of 12.97 mm. Keywords: Emulgel, kenikir leaf, acne, Staphylococcus aure

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Emulgel, kenikir leaf, acne, Staphylococcus aure
Subjects:	R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 02:57
Last Modified:	30 Nov 2022 02:57
URI:	http://repo.setiabudi.ac.id/id/eprint/5530

Actions (login required)

View Item