UJI AKTIVITAS ANTIBAKTERI SEDIAAN SERUM ANTI ACNE EKSTRAK DAUN BELIMBING WULUH (Averrhoa bilimbi L.) TERHADAP Staphylococcus aureus ATCC 25923

Naftalina, Naftalina (2022) UJI AKTIVITAS ANTIBAKTERI SEDIAAN SERUM ANTI ACNE EKSTRAK DAUN BELIMBING WULUH (Averrhoa bilimbi L.) TERHADAP Staphylococcus aureus ATCC 25923. Skripsi thesis, Universitas Setia Budi.

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Abstract

S. aureus bacterial infection can cause inflammation of the skin which is commonly known as acne. In a previous study, 5% concentration of starfruit leaf extract was able to inhibit S. aureus bacteria with an average inhibition zone of 27 mm. The purpose of this study was to make an anti-acne serum that has good physical quality and stability, and has antibacterial activity. Starfruit leaf powder was extracted using 96% ethanol by maceration method. Starfruit leaf extract with a concentration of 5% was formulated into serum preparations with variations of xanthan gum 1%, 1.2%, and 1.4%. Positive control is serum brand “A” and negative control is serum base. The physical quality test of the serum was in the form of organoleptic, homogeneity, pH, viscosity, and dispersibility, as well as a cycling test for stability test. Antibacterial activity against S. aureus ATCC 25923 was tested by disc diffusion method. The test results of pH, viscosity, dispersion, and antibacterial activity were analyzed using SPSS. The results showed that starfruit leaf extract could be formulated into an anti-acne serum with good physical quality and stability. Based on the organoleptic test, pH, viscosity, and dispersion, formula 1 is the best formula, and the inhibitory power is greater, although not significantly different. The diameters of the inhibition zones of formulas 1, 2, and 3 were 14.65 ± 0.25, 14.10 ± 0.29, and 14.16 ± 0.62, respectively. Keywords: starfruit leaf extract, serum preparation, anti-acne, Staphylococcus aureus.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	starfruit leaf extract, serum preparation, anti-acne, Staphylococcus aureus.
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 04:18
Last Modified:	30 Nov 2022 04:18
URI:	http://repo.setiabudi.ac.id/id/eprint/5571

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