Herowati, Rina (2018) Antibacterial Activity of Topical Polyherbal Formulation on Pseudomonas aeruginosa. Advanced Science Letters, 24 (1). pp. 121-124. ISSN 1936-6612
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Abstract
Pseudomonas aeruginosa is pathogen organism associated with a variety of skin and soft tissue infection, including diabetic foot ulcer. The aim of this study was to evaluate the antibacterial activity of polyherbal combination as well as its topical formulation in water in oil cream. The extraction was conducted by maceration in ethanol 96%. Five mixtures consisting of honey, Aloe vera, and ethanolic of extract Momordica charantia fruit, Curcuma longa rhizoma, as well as Smallantus sonchifolius leaves at different composition have been prepared (F1 to F5). The prepared mixtures were screened for their antibacterial activity against P. aeruginosa ATCC 27853 by agar well diffusion method, using cream contained of Neomycin sulfate and bacitracin as positive control. All mixtures were effective against P. aeruginosa ATCC 27853. Formula 5 consists of honey, Aloe vera, M. charantia fruit extract, C. longa rhizoma extract, and S. sonchifolius leaves extract (2.5; 2.5; 5; 5 and 5% respectively) was the most effective mixture. The w/o creams contained 7% of glycerine showed higher activity.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S2 Farmasi |
| Depositing User: | rina herowati |
| Date Deposited: | 03 Jul 2023 04:31 |
| Last Modified: | 03 Jul 2023 04:31 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/5924 |
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