UJI AKTIVITAS ANTIKOAGULAN EKSTRAK KULIT LABAN (Vitex pinnata Linn) SECARA IN VITRO

Jariani, Chesaria Pasti (2024) UJI AKTIVITAS ANTIKOAGULAN EKSTRAK KULIT LABAN (Vitex pinnata Linn) SECARA IN VITRO. Skripsi thesis, Universitas Setia Budi.

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Abstract

JARIANI, P.C., 2023, TESTING THE ANTICOAGULANT ACTIVITY OF LABAN SKIN EXTRACT (Vitex pinnata Linn) IN VITRO, Thesis, SETIA BUDI UNIVERSITY SURAKARTA FACULTY OF PHARMACY. Traditional healing practices in Central Kalimantan have been carried out for generations, especially by the Dayak tribe who live in the interior. One of the plants used by the Dayak people as traditional medicine is the Laban plant (Verbenaceae). This study aims to determine the anticoagulant activity of Laban peel extract and determine the time required for the blood clotting process. This research is an experimental study using the blood of white rats (Rattus norvegicus) by measuring the prothrombin time parameter in seconds and examining the clotting time which is used to determine the blood clotting period which is observed visually in the form of liquid, thick, very thick and very thick. freezes in minutes. The method used by Lee - White is to add 1 mL of blood to 120 μl of Laban bark extract (Vitex pinnata Linn) with concentrations of 10%, 30% and 50%, then determine the prothrombin time and clotting time. The test results showed that 96% laban bark extract had an anticoagulant effect and provided significant results on the % inhibition of coagulation with optimum activity, namely at a concentration of 50%. This research has proven that laban bark extract (Vitex pinnata Linn) has activity as an anticoagulant in vitro.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	darah, prothrombin time, clotting time, ekstrak kulit laban blood, prothrombin time, clotting time, laban bark extract
Subjects:	R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	USB
Date Deposited:	20 Jun 2024 06:12
Last Modified:	20 Jun 2024 06:12
URI:	http://repo.setiabudi.ac.id/id/eprint/6233

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