UJI AKTIVITAS ANTIBAKTERI GEL EKSTRAK RIMPANG KUNYIT (Curcuma domestica Val.) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 SECARA IN VIVO

OKTASIANA, Anita Rizki (2018) UJI AKTIVITAS ANTIBAKTERI GEL EKSTRAK RIMPANG KUNYIT (Curcuma domestica Val.) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 SECARA IN VIVO. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Various types of medicinal plants are known and widely used is turmeric. One of the active compounds that have antibacterial activity is curcumin. This study aims to determine the activity of antibacterial gel rhizome turmeric extract on the growth of Staphylococcus aureus ATCC 25923 in vivo. Turmeric powder is macerated with 70% ethanol, viscous extract is made gel preparation for antibacterial tested on rabbit backs infected with Staphylococcus aureus ATCC 25923 bacteria. Gel concentration 0.5%, 1%, 2%, 5%, positive control (Gentamicin 0.1 %), negative control. Physical quality test and gel stability were performed, the test result was statistically analyzed using two way (ANOVA) method. Observation of healing of rabbits seen from the length of time healing with loss of erythema, pus, scab, wound and accompanied by the growth of rabbit fur. Based on the research conducted, the preparation of effective turmeric rhizome gel extract has antibacterial activity against Staphylococcus aureus ATCC 25923 bacteria at 5% concentration. The results of physical quality analysis and gel stability treated statistically were nornal distributed. Keywords: Turmeric (Curcuma domestica Val.), Gel, Staphylococcus aureus ATCC 25923, in vivo

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Turmeric (Curcuma domestica Val.), Gel, Staphylococcus aureus ATCC 25923, in vivo
Subjects: R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 22 Feb 2019 07:38
Last Modified: 22 Feb 2019 07:38
URI: http://repo.setiabudi.ac.id/id/eprint/96

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